REMEDI Invited Speaker: Prof Marianne Verhaar May 23rd 9.15am

Seminar Center :Seminar Room, Biomedical Sciences Building

Name: Prof Marianne C. Verhaar

Title: Vascular Regenerative Medicine

Marianne C. Verhaar is Nephrologist and Professor of Experimental Nephrology at the University Medical Center Utrecht, the Netherlands. She is chair of the department of Nephrology and Hypertension and heads a research group in Experimental Nephrology. In 2015 she has been appointed chair of the UMC Utrecht Research Program Regenerative Medicine & Stem Cells.

Her research focuses on renal and vascular regeneration and involves translational studies from basic cell studies to animal experiments and clinical trials. General aim is to improve care for the patient with chronic kidney disease by developing new strategies to enhance protective mechanisms against microvascular dysfunction, atherosclerotic disease and chronic kidney disease, to enhance vascular and renal regeneration and to improve renal replacement therapies. Specific interests of the research group are: mechanisms underlying increased cardiovascular risk in chronic kidney disease; the relation between chronic kidney disease, microvascular dysfunction and heart failure; the role of stem and progenitor cells or cellular products in vascular and renal regeneration and their therapeutic potential in patients with cardiovascular and chronic kidney disease; development of renal organoids; development of a wearable (bio)artificial kidney.

Marianne Verhaar received several prestigious grants from the Netherlands Organisation for Scientific Research, the Dutch Heart Foundation and the Dutch Kidney Foundation and participates in several large (inter)national consortia. She is PI of the Juventas trial, the largest randomized, double-blind, placebo-controlled clinical trial to investigate bone marrow mononuclear cell therapy in patients with critical limb ischemia.