Centre for Chromosome Biology (CCB)
About UsThe Centre for Chromosome Biology (CCB) at NUI Galway in Ireland hosts an interactive network of researchers investigating topics linked to the biology of genomes. We are interested in understanding the molecular mechanisms underlying chromosome replication, segregation, repair, evolution, chromatin regulation and transcription.
“These processes are fundamental to our growing understanding of genetics and epigenetics, and have important implications for cancer and disease”.The Centre currently comprises 11 groups with over 90 researchers and support staff. We have a range of technologies available for studying chromosome biology at the molecular, cellular and organismal level.
Our Research Areas
Chromatin is the substrate for most processes that occur in the eukaryotic cell nucleus due to its role as the universal genome packaging state. The nucleosome is the fundamental repeating subunit of chromatin so it is unsurprising that the histone proteins organising this structure are highly conserved.Read More
Mitosis and meiosis are fundamental cellular processes required for the correct transmission of genetic material during cell division cycles. Centromeres are key regions of eukaryotic chromosomes where the kinetochore assembles to ensure proper chromosome segregation during mitosis and meiosis.Read More