Alimentary Glycoscience Research Cluster (AGRC)
Glycoscience is an interdisciplinary field of research focused on understanding the structures and roles of sugar chains attached to proteins and lipids in biological systems. Every living cell is coated with complex sugars (glycans) and glycan-binding proteins (lectins). Interactions between glycans and lectins on adjacent cells are involved in many essential biological processes including cell differentiation, immunity, reproduction, signaling and diseases such as cancer, inflammation, microbial infections. Also, a large proportion of naturally occurring proteins that are secreted or are part of the extracellular matrix are glycosylated.
Our Research Areas
The biomimc development team is using both phage-display and SELEX techniques to improve specificity to individual glycan epitopes.
Researching oligosaccharides as the third largest component of human milk in order to ensure optimal nutrition and development from the consumption of infant formula.
Polysaccharides are polymeric carbohydrate structures, formed of repeating units linked by glycosidic bonds.
Evolving new and novel enzymatic tools for the release of targeted glycan structures intact permitting whole glycan characterisation.