Biomaterials and Tissue Engineering
Biomaterials researchers are investigating the use of materials from
metals, to alloys, to smart polymers, important in biomedicine. Work is
also focused on the synthesis and characterisation of new polymers and
composites which have potential for use in new devices. Tissue
Engineering endeavours to persuade the body to heal itself through the
delivery of supporting structures to the appropriate site independently
or in synergy with cells and biomolecules. An understanding of natural
micro- and nano-architectures as well as cell behaviour leads to the
development of appropriate scaffolds for the next generation of
regenerative implants. The focus of this research is the development of
bioanalogous biomaterials for regenerative and clinical applications.
The development and synthesis of biomaterials is accomplished by
creating accurate ex vivo, in vitro and in vivo model systems for
specific clinical applications.
In recognition of the progress achieved thus far and the potential
impact of research in the field of biomaterials, Prof. Abhay Pandit has
recently received funding from Science Foundation Ireland (SFI) which
has led to the establishment of a strategic research cluster (SRC)
entitled 'Network of Excellence for Functional Biomaterials' (NFB), as an extension of the world-class biomedical research currently being carried out at the NCBES.
People
Publications
Director
Pandit , Abhay
Principal Investigators
Carroll , William
Garcia, Yolanda
Rochev , Yury
Wang , Wenxin
Zeugolis , Dimitrios
Collaborating Investigators
Dowd , Eilís
Finn, David
Fitzgerald, Una
Gallagher , William M
Kelly, Jack
McMahon , Siobhan
O'Brien , Timothy
Research Themes
Pandit , Abhay
Principal Investigators
Carroll , William
Garcia, Yolanda
Rochev , Yury
Wang , Wenxin
Zeugolis , Dimitrios
Collaborating Investigators
Dowd , Eilís
Finn, David
Fitzgerald, Una
Gallagher , William M
Kelly, Jack
McMahon , Siobhan
O'Brien , Timothy
Wall , Gerard J.
Post Doctoral Researchers
Cao, Hongliang
Helary, Christophe
Mahor, Sunil
Saeed, Aram
Yao, Li
Cao, Hongliang
Helary, Christophe
Mahor, Sunil
Saeed, Aram
Yao, Li
Zheng, Yu
Post Graduate Researchers
AbuRub, Mohammad
Aied, Ahmed
Alexander , Jennifer
Browne, Shane
Chan, Jeffrey
Collin , Estelle
Cunningham , Claire
Daly, Bill
Dash, Biraja Charan
Dong, Yixiao
Doody, Jaime
Fontana, Gianluca
Glynn, Gerald
Holladay, Carolyn
Kulkarni, Mangesh
Kumar, Pramod
Lang , Yvonne
Mathew, Asha
McArdle, Ciarstan
McGrath, Helen
Minor, William
Monaghan , Michael
Newland, Ben
O'Connor, Jacqueline
Redondo, Juan Alfonso
Satyam, Abhigyan
Tiong Hok Chuon, William
Ward , John
AbuRub, Mohammad
Aied, Ahmed
Alexander , Jennifer
Browne, Shane
Chan, Jeffrey
Collin , Estelle
Cunningham , Claire
Daly, Bill
Dash, Biraja Charan
Dong, Yixiao
Doody, Jaime
Fontana, Gianluca
Glynn, Gerald
Holladay, Carolyn
Kulkarni, Mangesh
Kumar, Pramod
Lang , Yvonne
Mathew, Asha
McArdle, Ciarstan
McGrath, Helen
Minor, William
Monaghan , Michael
Newland, Ben
O'Connor, Jacqueline
Redondo, Juan Alfonso
Satyam, Abhigyan
Tiong Hok Chuon, William
Ward , John
Musculoskeletal research at NFB involves devising strategies to regenerate the intervertebral disc and bone.
- Intervertebral Disc Regeneration
- Bone Regeneration
- Prosthetics Development
Neural regeneration research at NFB involves investigations into the
mechanisms of repair of peripheral nerve and spinal cord and the
development of functionalized scaffolds to aid this repair.
- Peripheral Nerve
- Spinal Cord
- Pain
- Neuroinflammatory Disease- Parkinson's Disease and Multiple Sclerosis
Research in soft tissue repair at NFB focuses on biomaterials for
reconstructive surgery and chronic wound healing as well as
investigating methods to treat the wounds in Recessive Dystrophic
Epidermolysis Bullosa.
- Wound Healing
- Reconstructive Surgery
- Wound Healing in Recessive Dystrophic Epidermolysis Bullosa
At NFB we are developing the next generation of cardiac patches and
grafts with the main focus being on the use of functionalized scaffolds
to regenerate infarcted myocardium and alleviating the effects of
ischemia in peripheral vascular disease.
2010
Dash, B.C., Rethore, G., Monaghan, M., Fitzgerald, K., Gallagher, W. and Pandit, A. 'The Influence of Size and Charge of Chitosan/polyglutamic Acid Hollow Spheres on Cellular Internalization, Viability and Blood Compatibility.' Biomaterials. 2010 (In Press ? 16th July 2010)
Yao, L., Billiar, K.L., Windebank, A.J. and Pandit, A. 'Multichannelled Collagen Conduits for Peripheral Nerve Regeneration: Design, Fabrication and Characterization.' Tissue Engineering Part C: Methods. 2010 (In Press - 4th June 2010)
Link to Pubmed
Newland, B., Tai, H., Zheng, Y., Velasco, D., Di Luca, A., Howdle, S.M., Alexander, C., Wang, W. and Pandit, A. ?A Highly Effective Gene Delivery Vector - Hyperbranched Poly(2-(Dimethylamino) Ethyl Methacrylate) From In-situ Deactivation Enhanced ATRP.' Chemical Communications. 2010: 46(26): 4698-4700
Link to Pubmed
Dong, Y., Gunning, P., Cao, H., Matthew, A., Newland, B., Saeed, A.O., Magnusson, J.P., Alexander, C., Tai, H., Pandit, A. and Wang, W. ?Dual Stimuli Responsive PEG Based Hyperbranched Polymers.' Polymer Chemistry. 2010 (In Press ? 21st April 2010)
Yao, L., de Ruiter, G.C.W., Wang, H., Knight, A.M., Spinner, R.J., Yaszemski, M.J. Windebank, A.J. and Pandit, A. ?Controlling Dispersion of Axonal Regeneration using a Multichannel Collagen Nerve Conduit.' Biomaterials. 2010: 31(22): 5789-5797.
Link to Pubmed
Abu-Rub, M.T., Zeugolis, D.I., McMahon, S., Windebank, A. and Pandit, A. ?Spinal Cord Injury In Vitro: Modelling Axon Growth Inhibition.' Drug Discovery Today. (In Press- 17th March 2010)
Link to Pubmed
Lareu, R.R., Zeugolis, D.I., Abu-Rub, M., Pandit, A., Raghunath, M. 'Essential Modification of the Sircol Collagen Assay for the Accurate Quantification of Collagen.' Acta Biomaterialia. 2010 (In Press 1st February 2010).
O'Rorke, S., Keeney, M. and Pandit, A. 'Non-Viral Polyplexes: Scaffold Mediated Delivery for Gene Therapy.' Progress in Polymer Science. 2010: 35(4): 441-458
O'Flynn, P.M., O'Sullivan, G. and Pandit, A.S. 'Geometric Variability of the Abdominal Aorta and its Major Peripheral Branches.' Annals of Biomedical Engineering. 2010: 38(3): 824-840
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Rethore, G. and Pandit, A. ?Use of Templates to Fabricate Nanoscale Spherical Structures for Defined Architectural Control.' Small. 2010: 6(4):488-498
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Kulkarni, M., Greiser, U., O'Brien, T. and Pandit, A. ?Liposomal Gene Delivery Mediated by Tissue-engineered Scaffolds.' Trends in Biotechnology. 2010: 28(1):28-36.
Link to Pubmed
Doleski, S., Yao, L., Pandit, A. and Elvira, C. 'NGF Release from Thermo-responsive Collagen-PolyNIPAam Polymer Networks Supports Neuronal Cell Growth and Differentiation.' Journal of Biomedical Materials Research: Part A. 2009 (In Press -27th August 2009)
Link to Pubmed
Holladay, C.A., O'Brien, T. and Pandit, A. 'Non-viral Gene Therapy for Myocardial Engineering.' WIREs Nanomedicine and Nanobiotechnology. 2010: 2(3): 232-248.
Link to Pubmed
2009
Keeney, M., van den Beucken, J.J., van der Kraan, P.M., Jansen, J.A., and Pandit, A. ?The Ability of a Collagen/Calcium Phosphate Scaffold to Act as its own Vector for Gene Delivery and to Promote Bone Formation via Transfection with VEGF165.' Biomaterials. 2010: 31(10): 2893-28902.
Link to Pubmed
Viñas-Castells, R., Holladay, C., di Luca, A., Diaz, V.M. and Pandit, A. 'Snail1 Down-Regulation using Small Interfering RNA Complexes Delivered through Collagen Scaffolds.' Bioconjugate Chemistry. 2009. 20(12): 2262-2269.
Link to Pubmed
McMahon, S.S., Albermann, S., Rooney, G.E., Moran, C., Hynes, J., Garcia, Y., Dockery, P., O'Brien, T., Windebank, A.J. and Barry FP. 'Effect of Cyclosporin A on Functional Recovery in the Spinal Cord following Contusion Injury.' Journal of Anatomy. 2009: 215(3): 267-279.
Link to Pubmed
O'Brien, B., Stinson, J. and Carroll, W. "Initial Exploration of Ti-Ta, Ti-Ta-Ir and Ti-Ir alloys: Candidate Materials for Coronary Stents." Acta Biomaterialia.
2008: 4(5): 1553-1559.
Link to Pubmed
Zeugolis, D.I., Paul, R. G. and Attenburrow, G. 'Extruded Collagen-polyethylene Glycol Fibers for Tissue Engineering Applications.' Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 2007: 85(2): 343 -352
Link to Pubmed
Zeugolis, D.I., Li, B., Lareu, R.R., Chan, C.K. and Raghunath, M. 'Collagen Solubility Testing, a Quality Assurance Step for Reproducible Electro-spun Nano-fibre Fabrication. A Technical Note.' Journal of Biomaterials Science: Polymer Edition. 2008: 19(10): 1307-1317.
Link to Pubmed
Zeugolis, D.I., Khew, S.T., Yew, E.S., Ekaputra, A.K., Tong, Y.W., Yung, L.Y., Hutmacher, D.W., Sheppard, C. and Raghunath, M. 'Electro-spinning of Pure Collagen Nano-fibres - Just an Expensive Way to make Gelatin?' Biomaterials. 2008: 29(15): 2293-2305.
Link to Pubmed
Zeugolis, D.I., Panengad, P.P., Yew, E.S., Sheppard, C., Phan, T.T. and Raghunath, M. 'An In Situ and In Vitro Investigation for the Transglutaminase Potential in Tissue Engineering.' Journal of Biomedical Materials Research: Part A. 2009: (In Press)
Link to Pubmed
Zeugolis, D.I., Paul, R.G. and Attenburrow, G. 'Cross-linking of Extruded Collagen Fibres ? A Biomimetic Three-dimensional Scaffold for Tissue Engineering Applications.' Journal of Biomedical Materials Research: Part A. 2009: 89(4): 895-908.
Link to Pubmed
Zeugolis, D.I., Paul, R.G. and Attenburrow, G. 'Extruded Collagen Fibres for Tissue-engineering Applications: Influence of Collagen Concentration and NaCl Amount.' Journal of Biomaterials Science: Polymer Edition. 2009: 20(2): 219-234.
Link to Pubmed
Tai, H., Wang, W., Vermonden, T., Heath, F., Hennink, W.E., Alexander, C., Shakesheff, K.M. and Howdle, S.M. 'Thermoresponsive and Photocrosslinkable PEGMEMA-PPGMA-EGDMA Copolymers from a One-step ATRP Synthesis.' Biomacromolecules. 2009: 10(4): 822-828.
Link to Pubmed
Wang, W. and Alexander, C. 'Self-immolative Polymers.' Angewandte Chemie. 2008: 47(41): 7804-7806
Link to Pubmed
Thermal responsive and photocrosslinkable dendritic copolymers from one-step ATRP synthesis.Tai, H.; Wang, W.; Vermonden, T.; Heath, F.; Hennink, W E.; Alexander, C.; Shakesheff, K. M. and Howdle, S. M. Biomacromol. 2009, 13;10(4):822-8.
Link to Pubmed
Wang, W., Liang, H., Al Ghanami, R.C., Hamilton, L., Fraylich, M., Shakesheff, K.M., Saunders, B. and Alexander, C. 'Biodegradable Thermoresponsive Microparticle Dispersions for Injectable Cell Delivery Prepared using a Single-Step Process.' Advanced Materials. 2009: 21: 1809-1813.
Link to Pubmed
Damodaran, G., Collighan, R., Griffin, M. Navsaria, H. and Pandit, A. ?Tailored Laminin-332 Alpha3 Sequence is Tethered through an Enzymatic Linker to a Collagen Scaffold to Promote Cellular Adhesion.' Acta Biomaterialia. 2009: 5(7): 2441-2450.
Link to Pubmed
Breen, A., O'Brien, T. and Pandit, A. ?Fibrin as a Delivery System for Therapeutic Drugs and Biomolecules.' Tissue Engineering. Part B, Reviews. 2009: 15(2): 201-214.
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Wallen, M. and Pandit, A. ?Developing Research Competencies through a Project-Based Tissue Engineering Module in the Biomedical Engineering Undergraduate Curriculum.' Proceedings of the Institution of Mechanical Engineers, Part H, Journal of Engineering in Medicine. 2009: 223(4): 443-448.
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Rethore, G., Matthew, A., Naik, H. and Pandit, A. ?Preparation of Chitosan/PolyGlutamic Spheres Based on the use of Polystyrene Template as a Non-viral Gene Carrier.' Tissue Engineering. Part C, Methods. 2009: 15(4): 605-613.
Link to Pubmed
Wallen, M. and Pandit, A. ?Encouraging Undergraduate Engineering Students towards Civic Engagement' European Journal of Engineering Education. 2009: 34(2): 141-148.
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Holladay, C., Keeney, M., Greiser, U., Murphy, M., O'Brien, T. and Pandit, A. ?Matrix Reservoir for Improved Control of Non-viral Gene Delivery.' Journal of Controlled Release. 2009: 136(3): 220?225.
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Henry, J.A. and Pandit, A. ?Perspective on Biomaterials used in the Surgical Treatment of Morbid Obesity.' Obesity Reviews. 2009: 10(3): 324-332.
Link to Pubmed
Breen, A., Dockery, P., O'Brien, T. and Pandit, A. 'Fibrin Scaffold Promotes Adenoviral Gene Transfer and Controlled Vector Delivery.' Journal of Biomedical Materials Research: Part A. 2009: 89(4):876-884
Link to Pubmed
Garcia, Y., Naik, H., Colligham, R., Griffin, M., Rodriguez-Cabello, J.C. and Pandit, A. ?In Vitro Characterization of a Collagen Scaffold Enzymatically Cross-linked with a Tailored Elastin-like Polymer.' Tissue Engineering. 2009: 15(4): 887-899.
Link to Pubmed
Kulkarni, M., Breen, A. Greiser, U., O'Brien, T. and Pandit, A. ?Fibrin-lipoplex System for Controlled Topical Delivery of Multiple Genes.' Biomacromolecules. 2009: 10(6): 1650-1654.
Link to Pubmed
Damodaran, G., Collighan, R., Griffin, M. and Pandit, A. 'Tethering a Laminin Peptide to a Crosslinked Collagen Scaffold for Biofunctionality.' Journal of Biomedical Materials Research: Part A. 2009: 89(4): 1001-1010.
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Burugapalli, K., Chan, J.C., Naik, H.K., Kelly, J.L. and Pandit, A. ?Tailoring the Properties of Cholecyst-derived Extracellular Matrix using Carbodiimide Cross-linking.' Journal of Biomaterial Science: Polymer Edition. 2009: 20(7): 1049-1063.
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Henry, J.A., Burugapalli, K., Neuenschwander, P. and Pandit, A. ?Structural Variants of Biodegradable Polyesterurethane In Vivo Evoke a Cellular and Angiogenic Response that is Dictated by Architecture.' Acta Biomateriala. 2009: 5(1): 29-42.
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Yao, L., Wang, S., Cui, W., Sherlock, R., O'Connell, C., Damodaran, G., Gorman, A., Windebank, A. and Pandit, A. ?Effect of Functionalized Micropatterned PLGA on Guided Neurite Growth.' Acta Biomaterialia. 2009: 5(2): 580-588.
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Yao, L., Damodaran, G., Nikolskaya, N., Gorman, A.M., Windebank, A. and Pandit, A. ?The Effect of Laminin Peptide Gradient in Enzymatically Cross-linked Collagen Scaffolds on Neurite Growth'. Journal of Biomedical Materials Research: Part A. 2009: 90(2): 894-890
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Yao, L., O'Brien, N., Windebank, A. and Pandit, A. ?Orienting Neurite Growth in Electrospun Fibrous Neural Conduits.' Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 2009: 90(2):483-491.
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Ball, M.D., O'Connor, D. and Pandit, A. ?Use of Tissue Transglutaminase and Fibronectin to Influence Osteoblast Responses to Tricalcium Phosphate Scaffolds.' Journal of Materials Science: Materials in Medicine. 2009: 20(1): 113-122.
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Keeney, M. and Pandit, A. ?The Osteochondral Junction and its Repair via Bi-phasic Tissue Engineering Scaffolds.' Tissue Engineering. Part B, Reviews. 2009: 15(1): 55-73.
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Ryan, G., McGarry, P., Pandit, A. and Apatsidis, D. ?Analysis of the Mechanical Behavior of a Titanium Scaffold with a Repeating Unit-cell Substructure'. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 2009: 90(2): 894-906
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2008
Zeugolis, D.I., Paul, R.G. and Attenburrow, G. 'Post Self-assembly Experimentation on Extruded Collagen Fibres for Tissue Engineering Applications.' Acta Biomaterialia. 2008: 4(6): 1646-1656.
Link to Pubmed
Zeugolis, D.I., Paul, R.G. and Attenburrow, G. 'Engineering Extruded Collagen Fibers for Biomedical Applications.' Journal of Applied Polymer Science. 2008: 108(5): 2886?2894.
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Zeugolis, D.I., Paul, R.G. and Attenburrow, G. 'Extruded collagen-polyethylene glycol fibres for tissue engineering applications.' Journal of Biomedical Materials Research-Part B, Applied Biomaterials, Vol. 85B, pp 343?352, (2008).
Link to Pubmed
Grignard, B., Jérôme, C., Calberg, C., Jérôme, R., Wang, W., Howdle, S.M. and Detrembleur, C. 'Copper Bromide Complexed by Fluorinated Macroligands: Towards Microspheres by ATRP of Vinyl Monomers in scCO2.' Chemical Communications. 2008: 3: 314-316.
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Fraylich, M., Wang, W., Shakesheff, K., Alexander, C. and Saunders, B. 'Poly(D,L-lactide-co-glycolide) Dispersions Containing Pluronics: From Particle Preparation to Temperature-triggered Aggregation.' Langmuir. 2008: 24(15): 7761?7768.
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Yang, J., Hasell, T., Wang. W, Li, J., Brown, P. D., Poliakoff, M., Lester, E., and Howdle, S. M., 'Preparation of Hybrid Polymer Nanocomposite Microparticles by a Nanoparticle Stabilised Dispersion Polymerisation.' Journal of Materials Chemistry. 2008: 18: 998 -1001.
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Zeugolis, D.I., Paul, R.G. and Attenburrow, G. 'Factors Influencing the Properties of Reconstituted Collagen Fibers Prior to Self-assembly: Animal Species and Collagen Extraction Method.' Journal of Biomedical Materials Research: Part A. 2008: 86(4): 892-904.
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Yang, J., Hasell, T., Wang, W. and Howdle, S.M. 'A Novel Synthetic Route to Metal-polymer Nanocomposites by In Situ Suspension and Bulk Polymerization.' European Polymer Journal. 2008: 44(5): 1331-1336
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Grignard, B., Jerôme, C., Calberg, C., Jérôme, R., Wang, W., Howdle, S.M. and Detrembleur, C. 'Copper Bromide Complexed by Fluorinated Macroligands: Towards Microspheres by ATRP of Vinyl Monomers in scCO2' Chemical Communications. 2008: 3: 314-316.
Link to Pubmed
Yang, J., Hasell, T., Wang. W, Li, J., Brown, P.D., Poliakoff, M., Lester, E. and Howdle, S. M. 'Preparation of Hybrid Polymer Nanocomposite Microparticles by a Nanoparticle Stabilised Dispersion Polymerisation.' Journal of Materials Chemistry. 2008: 18: 998 -1001.
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Magnússon, J.P., Khan, A., Pasparakis, G., Saeed, A.O., Wang, W., Alexander, C. 'Ion-responsive "isothermal" Responsive Polymers prepared in Water.' Journal of the American Chemical Society. 2008: 130(33): 10852-10853
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Burke, M., Clarke, B., Rochev, Y., Gorelov, A. and Carroll, W . 'Estimation of the Strength of Adhesion Between a Thermoresponsive Polymer Coating and Nitinol Wire.' Journal of Materials Science: Materials in Medicine. 2008: 19(5): 1971-1979.
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McLucas, E., Rochev, Y., Carroll, W.M. and Smith, T.J. 'Analysis of the Effects of Surface Treatments on Nickel Release from Nitinol Wires and their Impact on Candidate Gene Expression in Endothelial Cells. ' Journal of Materials Science: Materials in Medicine. 2008: 19(3): 975-980.
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Gundy, S., Manning, G., O'Connell, E., Ellä, V., Harwoko, M.S., Rochev, Y., Smith, T. and Barron, V. 'Human Coronary Artery Smooth Muscle Cell Response to a Novel PLA Textile/Fibrin Gel Composite Scaffold.' Acta Biomaterialia. 2008: 4(6): 1734-1744.
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Rooney, G. E., McMahon, S. S., Ritter, T., Garcia, Y., Moran, C., Madigan, N.N., Fluegel, A., Dockery, P., O'Brien, T., Howard, L, Windebank, A.J. and Barry, F.
'Neurotrophic Factor-Expressing Mesenchymal Stem Cell Survive Transplantation into the Contused Spinal Cord without Differentiating into Neural Cells.' Tissue Engineering. 2009: (In Press).
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O'Brien, B., Stinson, J. and Carroll, W. 'Development of a New Niobium-based Alloy for Vascular Stent Applications.' Journal of the Mechanical Behavior of Biomedical Materials. 2008: 1(4): 303-312.
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Shabalovskaya, S.A., Tian, H., Anderegg, J.W., Schryvers, D.U., Carroll, W.U. and Van Humbeeck, J.W.M. 'The Influence of Surface Oxides on the Distribution and Release of Nckel from Nitinol Wires.' Biomaterials. 2009: 30(4): 468-477.
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O'Brien, B.J., Stinson, J.S., Boismier, D.A. and Carroll, W.M. 'Characterization of an NbTaWZR Alloy Designed for Magnetic Resonance Angiography Compatible Stents.' Biomaterials. 2008: 29(34): 4540-4545.
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Gallaher H, Carroll, W. M., Dowd, M. and Rochev, Y. 'The Effects of Vindblastine on Endothelial Cells.' Endothelium. 2008: Vol 15(1): 9-15.
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Garcia, Y., Wilkins, B., Collighan, R.J., Griffin, M. and Pandit, A. ?Towards Development of a Dermal Rudiment for Enhanced Wound Healing.' Biomaterials. 2008: 29(7): 857-868.
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Breen, A.M., Dockery, P., O' Brien, T. and Pandit, A.S. ?The Use of Therapeutic Gene eNOS Delivered via a Fibrin Scaffold Enhances Wound Healing in a Compromised Wound Model.' Biomaterials. 2008: 29(21): 3143-3151.
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Burugapalli, K., Chan, J.C., Kelly, J.L. and Pandit, A. ?Buttressing Staples with Cholecyst-derived Extracellular Matrix (CEM) Reinforces Staple Lines in an Ex Vivo Peristaltic Inflation Model.' Obesity Surgery. 2008: 18(11):1418-1423
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Tiong, W.H., Damodaran, G., Naik, H., Kelly, J.L. and Pandit, A. ?Enhancing Amine Terminals in an Amine-deprived Collagen Matrix.' Langmuir. 2008: 24(20): 11752-11761.
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Chan, J.C., Burugapalli, K., Naik, H., Kelly, J.L. and Pandit A. ?Amine Functionalization of Cholecyst-derived Extracellular Matrix with Generation 1 PAMAM Dendrimer.' Biomacromolecules. 2008: 9(2):528-536.
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Breen, A., Dockery, P., O'Brien, T. and Pandit, A. 'Fibrin Scaffold Promotes Adenoviral Gene Transfer and Controlled Vector Delivery.' Journal of Biomedical Materials Research: Part A. 2008: 89(4): 876-884.
Link to Pubmed
Breen, A., McRedmond, G., Dockery, P., O'Brien, T. and Pandit, A. ?Assessment of Wound Healing in the Alloxan-induced Diabetic Rabbit Ear Model.' Journal of Investigative Surgery. 2008: 21(5):261-269.
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O'Halloran, D.O., Grad, S., Stoddart, M., Dockery, P., Alini, M. and Pandit, A.S. ?An Injectable Cross-linked Scaffold for Nucleus Pulposus Regeneration.' Biomaterials. 2008: 29(4): 438-447.
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Ryan, G., Pandit, A. and Apatsidis, D. 'Stress Distribution in the Intervertebral Disc Correlates with Strength Distribution in Subdiscal Trabecular Bone in the Porcine Lumbar Spine.' Clinical Biomechanics. 2008: 23(7): 859-869.
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Ryan, G.E., Pandit, A.S. and Apatsidis DP ?Porous Titanium Scaffolds Fabricated using a Rapid Prototyping and Powder Metallurgy Technique.' Biomaterials. 2008: 29(27): 3625-3635.
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Keeney, M., Collin, E. and Pandit, A. ?Multi-channelled Collagen-calcium Phosphate Scaffolds: Their Physical Properties and Human Cell Response.' Tissue Engineering. Part C, Methods. 2009: 15(2): 265-273.
Link to Pubmed
2007
Moran, M.T., Carroll, W.M., Gorelov, A., Rochev, Y. 'Intact Endothelial Cell Sheet Harvesting from Thermoresponsive Surfaces Coated with Cell Adhesion Promoters'. Journal of the Royal Society, Interface. 2007: 4(17): 1151-1157.
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Brody, S. and Pandit, A. ?Approaches to Heart Valve Tissue Engineering Scaffold Design.' Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 2007: 83(1): 16-43.
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Punchard, M.A., Stenson-Cox, C., O'Cearbhaill, E.D., Lyons, E., Gundy, S., Murphy, L., Pandit, A., McHugh, P.E. and Barron, V. ?Endothelial Cell Response to Biomechanical Forces under Simulated Vascular Loading Conditions.' Journal of Biomechanics. 2007: 40(14): 3146-3154.
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O'Flynn, P.M., Sullivan, G. and Pandit, A.S. ?Methods for Three-dimensional Geometric Characterization of the Arterial Vasculature.' Annals of Biomedical Engineering. 2007: 35(8): 1368-1381.
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Coburn, J.C., Brody, S., Billiar, K.L. and Pandit, A. ?Biaxial Mechanical Evaluation of Cholecyst-derived Extracellular Matrix: A Weakly Anisotropic Potential Tissue Engineered Biomaterial.' Journal of Biomedical Materials Research: Part A. 2007: 81(1): 250-256.
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Brody, S., McMahon, J., Yao, L., O'Brien, M., Dockery, P. and Pandit, A. ?The Effect of Cholecyst-Derived Extracellular Matrix on the Phenotypic Behaviour of Valvular Endothelial and Valvular Interstitial Cells.' Biomaterials. 2007: 28(8): 1461-1469.
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Burugapalli, K., Thapasimuttu, A., Chan, J.C., Yao, L., Brody, S., Kelly, J.L. and Pandit, A. ?Scaffold with a Natural Mesh-Like Architecture: Isolation, Structural and In Vitro Characterization.' Biomacromolecules. 2007: 8(3): 928-936.
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Henry, J.A., O'Sullivan, G. and Pandit, A.S. ?Using Computed Tomography Scans to Develop an Ex-vivo Gastric Model.' World Journal of Gastroenterology. 2007: 13(9): 1372-1377.
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Garcia, Y., Breen, A., Burugapalli, K., Dockery, P. and Pandit, A. ?Stereological Methods to Assess Tissue Response for Tissue-engineered Scaffolds.' Biomaterials. 2007: 28(2): 175-186.
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Garcia, Y., Collighan, R., Griffin, M. and Pandit, A. ?Assessment of Cell Viability in a Three-Dimensional Enzymatically Cross-linked Collagen Scaffold.' Journal of Materials Science. Materials in Medicine. 2007: 18(10): 1991-2001
Link to Pubmed
Henry, J.A., Simonet, M., Pandit, A. and Neuenschwander, P. ?Characterization of a Slowly Degrading Biodegradable Polyester-urethane for Tissue Engineering Scaffolds.' Journal of Biomedical Materials Research: Part A. 2007: 82(3): 669-679.
Link to Pubmed
Burugapalli, K. and Pandit, A. ?Characterization of Tissue Response and In Vivo Degradation of Cholecyst-derived Extracellular Matrix.' Biomacromolecules. 2007: 8(11): 3439-3451.
Link to Pubmed
O'Halloran, D.M. and Pandit, A.S. ?Tissue-engineering Approach to Regenerating the Intervertebral Disc.' Tissue Engineering. 2007: 13(8):1927-1954.
Link to Pubmed
Collaborations
Dash, B.C., Rethore, G., Monaghan, M., Fitzgerald, K., Gallagher, W. and Pandit, A. 'The Influence of Size and Charge of Chitosan/polyglutamic Acid Hollow Spheres on Cellular Internalization, Viability and Blood Compatibility.' Biomaterials. 2010 (In Press ? 16th July 2010)
Yao, L., Billiar, K.L., Windebank, A.J. and Pandit, A. 'Multichannelled Collagen Conduits for Peripheral Nerve Regeneration: Design, Fabrication and Characterization.' Tissue Engineering Part C: Methods. 2010 (In Press - 4th June 2010)
Link to Pubmed
Newland, B., Tai, H., Zheng, Y., Velasco, D., Di Luca, A., Howdle, S.M., Alexander, C., Wang, W. and Pandit, A. ?A Highly Effective Gene Delivery Vector - Hyperbranched Poly(2-(Dimethylamino) Ethyl Methacrylate) From In-situ Deactivation Enhanced ATRP.' Chemical Communications. 2010: 46(26): 4698-4700
Link to Pubmed
Dong, Y., Gunning, P., Cao, H., Matthew, A., Newland, B., Saeed, A.O., Magnusson, J.P., Alexander, C., Tai, H., Pandit, A. and Wang, W. ?Dual Stimuli Responsive PEG Based Hyperbranched Polymers.' Polymer Chemistry. 2010 (In Press ? 21st April 2010)
Yao, L., de Ruiter, G.C.W., Wang, H., Knight, A.M., Spinner, R.J., Yaszemski, M.J. Windebank, A.J. and Pandit, A. ?Controlling Dispersion of Axonal Regeneration using a Multichannel Collagen Nerve Conduit.' Biomaterials. 2010: 31(22): 5789-5797.
Link to Pubmed
Abu-Rub, M.T., Zeugolis, D.I., McMahon, S., Windebank, A. and Pandit, A. ?Spinal Cord Injury In Vitro: Modelling Axon Growth Inhibition.' Drug Discovery Today. (In Press- 17th March 2010)
Link to Pubmed
Lareu, R.R., Zeugolis, D.I., Abu-Rub, M., Pandit, A., Raghunath, M. 'Essential Modification of the Sircol Collagen Assay for the Accurate Quantification of Collagen.' Acta Biomaterialia. 2010 (In Press 1st February 2010).
O'Rorke, S., Keeney, M. and Pandit, A. 'Non-Viral Polyplexes: Scaffold Mediated Delivery for Gene Therapy.' Progress in Polymer Science. 2010: 35(4): 441-458
O'Flynn, P.M., O'Sullivan, G. and Pandit, A.S. 'Geometric Variability of the Abdominal Aorta and its Major Peripheral Branches.' Annals of Biomedical Engineering. 2010: 38(3): 824-840
Link to Pubmed
Rethore, G. and Pandit, A. ?Use of Templates to Fabricate Nanoscale Spherical Structures for Defined Architectural Control.' Small. 2010: 6(4):488-498
Link to Pubmed
Kulkarni, M., Greiser, U., O'Brien, T. and Pandit, A. ?Liposomal Gene Delivery Mediated by Tissue-engineered Scaffolds.' Trends in Biotechnology. 2010: 28(1):28-36.
Link to Pubmed
Doleski, S., Yao, L., Pandit, A. and Elvira, C. 'NGF Release from Thermo-responsive Collagen-PolyNIPAam Polymer Networks Supports Neuronal Cell Growth and Differentiation.' Journal of Biomedical Materials Research: Part A. 2009 (In Press -27th August 2009)
Link to Pubmed
Holladay, C.A., O'Brien, T. and Pandit, A. 'Non-viral Gene Therapy for Myocardial Engineering.' WIREs Nanomedicine and Nanobiotechnology. 2010: 2(3): 232-248.
Link to Pubmed
Keeney, M., van den Beucken, J.J., van der Kraan, P.M., Jansen, J.A., and Pandit, A. ?The Ability of a Collagen/Calcium Phosphate Scaffold to Act as its own Vector for Gene Delivery and to Promote Bone Formation via Transfection with VEGF165.' Biomaterials. 2010: 31(10): 2893-28902.
Link to Pubmed
Viñas-Castells, R., Holladay, C., di Luca, A., Diaz, V.M. and Pandit, A. 'Snail1 Down-Regulation using Small Interfering RNA Complexes Delivered through Collagen Scaffolds.' Bioconjugate Chemistry. 2009. 20(12): 2262-2269.
Link to Pubmed
McMahon, S.S., Albermann, S., Rooney, G.E., Moran, C., Hynes, J., Garcia, Y., Dockery, P., O'Brien, T., Windebank, A.J. and Barry FP. 'Effect of Cyclosporin A on Functional Recovery in the Spinal Cord following Contusion Injury.' Journal of Anatomy. 2009: 215(3): 267-279.
Link to Pubmed
O'Brien, B., Stinson, J. and Carroll, W. "Initial Exploration of Ti-Ta, Ti-Ta-Ir and Ti-Ir alloys: Candidate Materials for Coronary Stents." Acta Biomaterialia.
2008: 4(5): 1553-1559.
Link to Pubmed
Zeugolis, D.I., Paul, R. G. and Attenburrow, G. 'Extruded Collagen-polyethylene Glycol Fibers for Tissue Engineering Applications.' Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 2007: 85(2): 343 -352
Link to Pubmed
Zeugolis, D.I., Li, B., Lareu, R.R., Chan, C.K. and Raghunath, M. 'Collagen Solubility Testing, a Quality Assurance Step for Reproducible Electro-spun Nano-fibre Fabrication. A Technical Note.' Journal of Biomaterials Science: Polymer Edition. 2008: 19(10): 1307-1317.
Link to Pubmed
Zeugolis, D.I., Khew, S.T., Yew, E.S., Ekaputra, A.K., Tong, Y.W., Yung, L.Y., Hutmacher, D.W., Sheppard, C. and Raghunath, M. 'Electro-spinning of Pure Collagen Nano-fibres - Just an Expensive Way to make Gelatin?' Biomaterials. 2008: 29(15): 2293-2305.
Link to Pubmed
Zeugolis, D.I., Panengad, P.P., Yew, E.S., Sheppard, C., Phan, T.T. and Raghunath, M. 'An In Situ and In Vitro Investigation for the Transglutaminase Potential in Tissue Engineering.' Journal of Biomedical Materials Research: Part A. 2009: (In Press)
Link to Pubmed
Zeugolis, D.I., Paul, R.G. and Attenburrow, G. 'Cross-linking of Extruded Collagen Fibres ? A Biomimetic Three-dimensional Scaffold for Tissue Engineering Applications.' Journal of Biomedical Materials Research: Part A. 2009: 89(4): 895-908.
Link to Pubmed
Zeugolis, D.I., Paul, R.G. and Attenburrow, G. 'Extruded Collagen Fibres for Tissue-engineering Applications: Influence of Collagen Concentration and NaCl Amount.' Journal of Biomaterials Science: Polymer Edition. 2009: 20(2): 219-234.
Link to Pubmed
Tai, H., Wang, W., Vermonden, T., Heath, F., Hennink, W.E., Alexander, C., Shakesheff, K.M. and Howdle, S.M. 'Thermoresponsive and Photocrosslinkable PEGMEMA-PPGMA-EGDMA Copolymers from a One-step ATRP Synthesis.' Biomacromolecules. 2009: 10(4): 822-828.
Link to Pubmed
Wang, W. and Alexander, C. 'Self-immolative Polymers.' Angewandte Chemie. 2008: 47(41): 7804-7806
Link to Pubmed
Thermal responsive and photocrosslinkable dendritic copolymers from one-step ATRP synthesis.Tai, H.; Wang, W.; Vermonden, T.; Heath, F.; Hennink, W E.; Alexander, C.; Shakesheff, K. M. and Howdle, S. M. Biomacromol. 2009, 13;10(4):822-8.
Link to Pubmed
Wang, W., Liang, H., Al Ghanami, R.C., Hamilton, L., Fraylich, M., Shakesheff, K.M., Saunders, B. and Alexander, C. 'Biodegradable Thermoresponsive Microparticle Dispersions for Injectable Cell Delivery Prepared using a Single-Step Process.' Advanced Materials. 2009: 21: 1809-1813.
Link to Pubmed
Damodaran, G., Collighan, R., Griffin, M. Navsaria, H. and Pandit, A. ?Tailored Laminin-332 Alpha3 Sequence is Tethered through an Enzymatic Linker to a Collagen Scaffold to Promote Cellular Adhesion.' Acta Biomaterialia. 2009: 5(7): 2441-2450.
Link to Pubmed
Breen, A., O'Brien, T. and Pandit, A. ?Fibrin as a Delivery System for Therapeutic Drugs and Biomolecules.' Tissue Engineering. Part B, Reviews. 2009: 15(2): 201-214.
Link to Pubmed
Wallen, M. and Pandit, A. ?Developing Research Competencies through a Project-Based Tissue Engineering Module in the Biomedical Engineering Undergraduate Curriculum.' Proceedings of the Institution of Mechanical Engineers, Part H, Journal of Engineering in Medicine. 2009: 223(4): 443-448.
Link to Pubmed
Rethore, G., Matthew, A., Naik, H. and Pandit, A. ?Preparation of Chitosan/PolyGlutamic Spheres Based on the use of Polystyrene Template as a Non-viral Gene Carrier.' Tissue Engineering. Part C, Methods. 2009: 15(4): 605-613.
Link to Pubmed
Wallen, M. and Pandit, A. ?Encouraging Undergraduate Engineering Students towards Civic Engagement' European Journal of Engineering Education. 2009: 34(2): 141-148.
Link to Pubmed
Holladay, C., Keeney, M., Greiser, U., Murphy, M., O'Brien, T. and Pandit, A. ?Matrix Reservoir for Improved Control of Non-viral Gene Delivery.' Journal of Controlled Release. 2009: 136(3): 220?225.
Link to Pubmed
Henry, J.A. and Pandit, A. ?Perspective on Biomaterials used in the Surgical Treatment of Morbid Obesity.' Obesity Reviews. 2009: 10(3): 324-332.
Link to Pubmed
Breen, A., Dockery, P., O'Brien, T. and Pandit, A. 'Fibrin Scaffold Promotes Adenoviral Gene Transfer and Controlled Vector Delivery.' Journal of Biomedical Materials Research: Part A. 2009: 89(4):876-884
Link to Pubmed
Garcia, Y., Naik, H., Colligham, R., Griffin, M., Rodriguez-Cabello, J.C. and Pandit, A. ?In Vitro Characterization of a Collagen Scaffold Enzymatically Cross-linked with a Tailored Elastin-like Polymer.' Tissue Engineering. 2009: 15(4): 887-899.
Link to Pubmed
Kulkarni, M., Breen, A. Greiser, U., O'Brien, T. and Pandit, A. ?Fibrin-lipoplex System for Controlled Topical Delivery of Multiple Genes.' Biomacromolecules. 2009: 10(6): 1650-1654.
Link to Pubmed
Damodaran, G., Collighan, R., Griffin, M. and Pandit, A. 'Tethering a Laminin Peptide to a Crosslinked Collagen Scaffold for Biofunctionality.' Journal of Biomedical Materials Research: Part A. 2009: 89(4): 1001-1010.
Link to Pubmed
Burugapalli, K., Chan, J.C., Naik, H.K., Kelly, J.L. and Pandit, A. ?Tailoring the Properties of Cholecyst-derived Extracellular Matrix using Carbodiimide Cross-linking.' Journal of Biomaterial Science: Polymer Edition. 2009: 20(7): 1049-1063.
Link to Pubmed
Henry, J.A., Burugapalli, K., Neuenschwander, P. and Pandit, A. ?Structural Variants of Biodegradable Polyesterurethane In Vivo Evoke a Cellular and Angiogenic Response that is Dictated by Architecture.' Acta Biomateriala. 2009: 5(1): 29-42.
Link to Pubmed
Yao, L., Wang, S., Cui, W., Sherlock, R., O'Connell, C., Damodaran, G., Gorman, A., Windebank, A. and Pandit, A. ?Effect of Functionalized Micropatterned PLGA on Guided Neurite Growth.' Acta Biomaterialia. 2009: 5(2): 580-588.
Link to Pubmed
Yao, L., Damodaran, G., Nikolskaya, N., Gorman, A.M., Windebank, A. and Pandit, A. ?The Effect of Laminin Peptide Gradient in Enzymatically Cross-linked Collagen Scaffolds on Neurite Growth'. Journal of Biomedical Materials Research: Part A. 2009: 90(2): 894-890
Link to Pubmed
Yao, L., O'Brien, N., Windebank, A. and Pandit, A. ?Orienting Neurite Growth in Electrospun Fibrous Neural Conduits.' Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 2009: 90(2):483-491.
Link to Pubmed
Ball, M.D., O'Connor, D. and Pandit, A. ?Use of Tissue Transglutaminase and Fibronectin to Influence Osteoblast Responses to Tricalcium Phosphate Scaffolds.' Journal of Materials Science: Materials in Medicine. 2009: 20(1): 113-122.
Link to Pubmed
Keeney, M. and Pandit, A. ?The Osteochondral Junction and its Repair via Bi-phasic Tissue Engineering Scaffolds.' Tissue Engineering. Part B, Reviews. 2009: 15(1): 55-73.
Link to Pubmed
Ryan, G., McGarry, P., Pandit, A. and Apatsidis, D. ?Analysis of the Mechanical Behavior of a Titanium Scaffold with a Repeating Unit-cell Substructure'. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 2009: 90(2): 894-906
Link to Pubmed
Zeugolis, D.I., Paul, R.G. and Attenburrow, G. 'Post Self-assembly Experimentation on Extruded Collagen Fibres for Tissue Engineering Applications.' Acta Biomaterialia. 2008: 4(6): 1646-1656.
Link to Pubmed
Zeugolis, D.I., Paul, R.G. and Attenburrow, G. 'Engineering Extruded Collagen Fibers for Biomedical Applications.' Journal of Applied Polymer Science. 2008: 108(5): 2886?2894.
Link to Pubmed
Zeugolis, D.I., Paul, R.G. and Attenburrow, G. 'Extruded collagen-polyethylene glycol fibres for tissue engineering applications.' Journal of Biomedical Materials Research-Part B, Applied Biomaterials, Vol. 85B, pp 343?352, (2008).
Link to Pubmed
Grignard, B., Jérôme, C., Calberg, C., Jérôme, R., Wang, W., Howdle, S.M. and Detrembleur, C. 'Copper Bromide Complexed by Fluorinated Macroligands: Towards Microspheres by ATRP of Vinyl Monomers in scCO2.' Chemical Communications. 2008: 3: 314-316.
Link to Pubmed
Fraylich, M., Wang, W., Shakesheff, K., Alexander, C. and Saunders, B. 'Poly(D,L-lactide-co-glycolide) Dispersions Containing Pluronics: From Particle Preparation to Temperature-triggered Aggregation.' Langmuir. 2008: 24(15): 7761?7768.
Link to Pubmed
Yang, J., Hasell, T., Wang. W, Li, J., Brown, P. D., Poliakoff, M., Lester, E., and Howdle, S. M., 'Preparation of Hybrid Polymer Nanocomposite Microparticles by a Nanoparticle Stabilised Dispersion Polymerisation.' Journal of Materials Chemistry. 2008: 18: 998 -1001.
Link to Pubmed
Zeugolis, D.I., Paul, R.G. and Attenburrow, G. 'Factors Influencing the Properties of Reconstituted Collagen Fibers Prior to Self-assembly: Animal Species and Collagen Extraction Method.' Journal of Biomedical Materials Research: Part A. 2008: 86(4): 892-904.
Link to Pubmed
Yang, J., Hasell, T., Wang, W. and Howdle, S.M. 'A Novel Synthetic Route to Metal-polymer Nanocomposites by In Situ Suspension and Bulk Polymerization.' European Polymer Journal. 2008: 44(5): 1331-1336
Link to Pubmed
Grignard, B., Jerôme, C., Calberg, C., Jérôme, R., Wang, W., Howdle, S.M. and Detrembleur, C. 'Copper Bromide Complexed by Fluorinated Macroligands: Towards Microspheres by ATRP of Vinyl Monomers in scCO2' Chemical Communications. 2008: 3: 314-316.
Link to Pubmed
Yang, J., Hasell, T., Wang. W, Li, J., Brown, P.D., Poliakoff, M., Lester, E. and Howdle, S. M. 'Preparation of Hybrid Polymer Nanocomposite Microparticles by a Nanoparticle Stabilised Dispersion Polymerisation.' Journal of Materials Chemistry. 2008: 18: 998 -1001.
Link to Pubmed
Magnússon, J.P., Khan, A., Pasparakis, G., Saeed, A.O., Wang, W., Alexander, C. 'Ion-responsive "isothermal" Responsive Polymers prepared in Water.' Journal of the American Chemical Society. 2008: 130(33): 10852-10853
Link to Pubmed
Burke, M., Clarke, B., Rochev, Y., Gorelov, A. and Carroll, W . 'Estimation of the Strength of Adhesion Between a Thermoresponsive Polymer Coating and Nitinol Wire.' Journal of Materials Science: Materials in Medicine. 2008: 19(5): 1971-1979.
Link to Pubmed
McLucas, E., Rochev, Y., Carroll, W.M. and Smith, T.J. 'Analysis of the Effects of Surface Treatments on Nickel Release from Nitinol Wires and their Impact on Candidate Gene Expression in Endothelial Cells. ' Journal of Materials Science: Materials in Medicine. 2008: 19(3): 975-980.
Link to Pubmed
Gundy, S., Manning, G., O'Connell, E., Ellä, V., Harwoko, M.S., Rochev, Y., Smith, T. and Barron, V. 'Human Coronary Artery Smooth Muscle Cell Response to a Novel PLA Textile/Fibrin Gel Composite Scaffold.' Acta Biomaterialia. 2008: 4(6): 1734-1744.
Link to Pubmed
Rooney, G. E., McMahon, S. S., Ritter, T., Garcia, Y., Moran, C., Madigan, N.N., Fluegel, A., Dockery, P., O'Brien, T., Howard, L, Windebank, A.J. and Barry, F.
'Neurotrophic Factor-Expressing Mesenchymal Stem Cell Survive Transplantation into the Contused Spinal Cord without Differentiating into Neural Cells.' Tissue Engineering. 2009: (In Press).
Link to Pubmed
O'Brien, B., Stinson, J. and Carroll, W. 'Development of a New Niobium-based Alloy for Vascular Stent Applications.' Journal of the Mechanical Behavior of Biomedical Materials. 2008: 1(4): 303-312.
Link to Pubmed
Shabalovskaya, S.A., Tian, H., Anderegg, J.W., Schryvers, D.U., Carroll, W.U. and Van Humbeeck, J.W.M. 'The Influence of Surface Oxides on the Distribution and Release of Nckel from Nitinol Wires.' Biomaterials. 2009: 30(4): 468-477.
Link to Pubmed
O'Brien, B.J., Stinson, J.S., Boismier, D.A. and Carroll, W.M. 'Characterization of an NbTaWZR Alloy Designed for Magnetic Resonance Angiography Compatible Stents.' Biomaterials. 2008: 29(34): 4540-4545.
Link to Pubmed
Gallaher H, Carroll, W. M., Dowd, M. and Rochev, Y. 'The Effects of Vindblastine on Endothelial Cells.' Endothelium. 2008: Vol 15(1): 9-15.
Link to Pubmed
Garcia, Y., Wilkins, B., Collighan, R.J., Griffin, M. and Pandit, A. ?Towards Development of a Dermal Rudiment for Enhanced Wound Healing.' Biomaterials. 2008: 29(7): 857-868.
Link to Pubmed
Breen, A.M., Dockery, P., O' Brien, T. and Pandit, A.S. ?The Use of Therapeutic Gene eNOS Delivered via a Fibrin Scaffold Enhances Wound Healing in a Compromised Wound Model.' Biomaterials. 2008: 29(21): 3143-3151.
Link to Pubmed
Burugapalli, K., Chan, J.C., Kelly, J.L. and Pandit, A. ?Buttressing Staples with Cholecyst-derived Extracellular Matrix (CEM) Reinforces Staple Lines in an Ex Vivo Peristaltic Inflation Model.' Obesity Surgery. 2008: 18(11):1418-1423
Link to Pubmed
Tiong, W.H., Damodaran, G., Naik, H., Kelly, J.L. and Pandit, A. ?Enhancing Amine Terminals in an Amine-deprived Collagen Matrix.' Langmuir. 2008: 24(20): 11752-11761.
Link to Pubmed
Chan, J.C., Burugapalli, K., Naik, H., Kelly, J.L. and Pandit A. ?Amine Functionalization of Cholecyst-derived Extracellular Matrix with Generation 1 PAMAM Dendrimer.' Biomacromolecules. 2008: 9(2):528-536.
Link to Pubmed
Breen, A., Dockery, P., O'Brien, T. and Pandit, A. 'Fibrin Scaffold Promotes Adenoviral Gene Transfer and Controlled Vector Delivery.' Journal of Biomedical Materials Research: Part A. 2008: 89(4): 876-884.
Link to Pubmed
Breen, A., McRedmond, G., Dockery, P., O'Brien, T. and Pandit, A. ?Assessment of Wound Healing in the Alloxan-induced Diabetic Rabbit Ear Model.' Journal of Investigative Surgery. 2008: 21(5):261-269.
Link to Pubmed
O'Halloran, D.O., Grad, S., Stoddart, M., Dockery, P., Alini, M. and Pandit, A.S. ?An Injectable Cross-linked Scaffold for Nucleus Pulposus Regeneration.' Biomaterials. 2008: 29(4): 438-447.
Link to Pubmed
Ryan, G., Pandit, A. and Apatsidis, D. 'Stress Distribution in the Intervertebral Disc Correlates with Strength Distribution in Subdiscal Trabecular Bone in the Porcine Lumbar Spine.' Clinical Biomechanics. 2008: 23(7): 859-869.
Link to Pubmed
Ryan, G.E., Pandit, A.S. and Apatsidis DP ?Porous Titanium Scaffolds Fabricated using a Rapid Prototyping and Powder Metallurgy Technique.' Biomaterials. 2008: 29(27): 3625-3635.
Link to Pubmed
Keeney, M., Collin, E. and Pandit, A. ?Multi-channelled Collagen-calcium Phosphate Scaffolds: Their Physical Properties and Human Cell Response.' Tissue Engineering. Part C, Methods. 2009: 15(2): 265-273.
Link to Pubmed
Moran, M.T., Carroll, W.M., Gorelov, A., Rochev, Y. 'Intact Endothelial Cell Sheet Harvesting from Thermoresponsive Surfaces Coated with Cell Adhesion Promoters'. Journal of the Royal Society, Interface. 2007: 4(17): 1151-1157.
Link to Pubmed
Brody, S. and Pandit, A. ?Approaches to Heart Valve Tissue Engineering Scaffold Design.' Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 2007: 83(1): 16-43.
Link to Pubmed
Punchard, M.A., Stenson-Cox, C., O'Cearbhaill, E.D., Lyons, E., Gundy, S., Murphy, L., Pandit, A., McHugh, P.E. and Barron, V. ?Endothelial Cell Response to Biomechanical Forces under Simulated Vascular Loading Conditions.' Journal of Biomechanics. 2007: 40(14): 3146-3154.
Link to Pubmed
O'Flynn, P.M., Sullivan, G. and Pandit, A.S. ?Methods for Three-dimensional Geometric Characterization of the Arterial Vasculature.' Annals of Biomedical Engineering. 2007: 35(8): 1368-1381.
Link to Pubmed
Coburn, J.C., Brody, S., Billiar, K.L. and Pandit, A. ?Biaxial Mechanical Evaluation of Cholecyst-derived Extracellular Matrix: A Weakly Anisotropic Potential Tissue Engineered Biomaterial.' Journal of Biomedical Materials Research: Part A. 2007: 81(1): 250-256.
Link to Pubmed
Brody, S., McMahon, J., Yao, L., O'Brien, M., Dockery, P. and Pandit, A. ?The Effect of Cholecyst-Derived Extracellular Matrix on the Phenotypic Behaviour of Valvular Endothelial and Valvular Interstitial Cells.' Biomaterials. 2007: 28(8): 1461-1469.
Link to Pubmed
Burugapalli, K., Thapasimuttu, A., Chan, J.C., Yao, L., Brody, S., Kelly, J.L. and Pandit, A. ?Scaffold with a Natural Mesh-Like Architecture: Isolation, Structural and In Vitro Characterization.' Biomacromolecules. 2007: 8(3): 928-936.
Link to Pubmed
Henry, J.A., O'Sullivan, G. and Pandit, A.S. ?Using Computed Tomography Scans to Develop an Ex-vivo Gastric Model.' World Journal of Gastroenterology. 2007: 13(9): 1372-1377.
Link to Pubmed
Garcia, Y., Breen, A., Burugapalli, K., Dockery, P. and Pandit, A. ?Stereological Methods to Assess Tissue Response for Tissue-engineered Scaffolds.' Biomaterials. 2007: 28(2): 175-186.
Link to Pubmed
Garcia, Y., Collighan, R., Griffin, M. and Pandit, A. ?Assessment of Cell Viability in a Three-Dimensional Enzymatically Cross-linked Collagen Scaffold.' Journal of Materials Science. Materials in Medicine. 2007: 18(10): 1991-2001
Link to Pubmed
Henry, J.A., Simonet, M., Pandit, A. and Neuenschwander, P. ?Characterization of a Slowly Degrading Biodegradable Polyester-urethane for Tissue Engineering Scaffolds.' Journal of Biomedical Materials Research: Part A. 2007: 82(3): 669-679.
Link to Pubmed
Burugapalli, K. and Pandit, A. ?Characterization of Tissue Response and In Vivo Degradation of Cholecyst-derived Extracellular Matrix.' Biomacromolecules. 2007: 8(11): 3439-3451.
Link to Pubmed
O'Halloran, D.M. and Pandit, A.S. ?Tissue-engineering Approach to Regenerating the Intervertebral Disc.' Tissue Engineering. 2007: 13(8):1927-1954.
Link to Pubmed
Academic
The Network of Excellence for Functional Biomaterials has a significant number of scientific collaborators across the world and throughout many facets of research related to biomaterials.The NFB Strategic Research Cluster (SRC) was set up in 2007 with funding from Science Foundation Ireland (SFI) to research and develop an advanced and extensive research programme targeted at specific biomedical applications. The NFB also has other academic collaborators in programmes which are funded through other organisations including the European Union (EU), Irish Research Council Science Engineering and Technology programme (IRCSET), the Higher Education Authority (HEA), the Health Research Board (HRB), the Welcome Trust, DEBRA and Enterprise Ireland (EI) amongst others.
NFB is a participant in the EU FP7 funded 'Disc Regeneration' programme. This research aims to develop therapies for intervertebral disc disease which affects more than 40% of European adults at some stage during their lives.
Industry
Vornia Biomaterials, Galway
The Network of Excellence for Functional Biomaterials has a significant number of scientific collaborators across the world and throughout many facets of research related to biomaterials.The NFB Strategic Research Cluster (SRC) was set up in 2007 with funding from Science Foundation Ireland (SFI) to research and develop an advanced and extensive research programme targeted at specific biomedical applications. The NFB also has other academic collaborators in programmes which are funded through other organisations including the European Union (EU), Irish Research Council Science Engineering and Technology programme (IRCSET), the Higher Education Authority (HEA), the Health Research Board (HRB), the Welcome Trust, DEBRA and Enterprise Ireland (EI) amongst others.
Collaborative Centre for Functional Biomaterials, University of Ulster
NFB is a participant in the EU FP7 funded 'Disc Regeneration' programme. This research aims to develop therapies for intervertebral disc disease which affects more than 40% of European adults at some stage during their lives.
Industry
Vornia Biomaterials, Galway
