Our People

Biosketch
Dr. Yury Rochev obtained an honors Master of Science degree in Physics (1984) at Moscow State University, Biophysical Department, Russia. In 1990 he was awarded a Doctorate in Biophysics from the Institute of Biological Physics, the Soviet Academy of Science, at Pushchino (Moscow region). He worked at the Institute of Biological Physics at the Soviet Academy of Science, Pushchino, (later the Institute of Theoretical and Experimental Biophysics, the Russian Academy of Science), Pushchino State University, from 1984 to 1998. His appointments include holding posts of Institute Deputy Director, Vice Rector for Academic affairs, and Chair of Advanced Biomaterials and Tissue engineering. In 1998, he took up a research fellowship position at the Department of Chemistry, NUI Dublin, before taking up his present appointment as Senior Researcher in the Biomaterials Cluster, at the National Centre for Biomedical Engineering Science (NCBES) at NUI Galway. He was appointed as a Lecturer in Biomedical Engineering Science at the NCBES in 2007. Currently, he is coordinator of the M.Sc. in Biomedical Science course.
 
His current research interests include design and development of new smart biomaterials, polymer-based drug delivery systems, tissue engineering products, as well as nano- and micro-scale characterisation of biomaterials and medical devices. As the Biomaterials senior researcher he has managed the research activities of the Biomaterials cluster since 2002. He has published more than 120 journal articles, book chapters, conference and workshops abstracts and papers. Dr. Rochev is involved in several national and international collaborative research projects in biomaterials and tissue engineering. Dr. Rochev is involved in a number of industrial research collaborations, including a major collaborative research program with Boston Scientific Ireland.
Research Interests
Dr. Yury Rochev's current research interests include the design and development of new smart biomaterials, polymer-based drug delivery systems, tissue engineering products, as well as nano- and micro-scale characterization of biomaterials and medical devices, particular cardiovascular stents. His three main research areas are (1) design and development of smart stimulus-responsive biomaterials for cytotechnology and drug delivery; (2) characterization of biomaterials and medical devices at the nano- and micro-scale level, as well as correlation between physical and chemical characteristics of biomaterials and cellular responses; (3) design and development of new composite ?intelligence? 3-D scaffolds for tissue engineering and drug delivery.
Key Publications
Babu R. Prasad. B, Terry Smith, Michael A. Brook, Shigui Zhao, Heather Sheardown,  Yuri Rochev , Controlling Cellular Activity with Silicone Surface Roughness ,  Colloids Surf B Biointerfaces. 2010 Jul 1;78(2):237-42. Epub 2010 Mar 19.
 
Prasad BR, Nikolskaya N, Connolly D, Smith TJ, Byrne SJ, Gérard VA, Gun'ko YK, Rochev Y, Long-term exposure of CdTe quantum dots on PC12 cellular activity and the determination of optimum non-toxic concentrations for biological use, J Nanobiotechnology. 2010 Mar 25;8:7.
 
Gallagher H, Carroll WM, Rochev Y. The effects of vinblastine on smooth muscle cells in vitro: evaluation of a therapeutic window for the treatment of restenosis. J Cardiovasc Pharmacol. 2010 Apr;55(4):399-407.
 
Polarity Assessment of Thermoresponsive Poly(NIPAM-co-NtBA) Copolymer Films Using Fluorescence Methods. Szczupak B, Ryder AG, Togashi DM, Klymchenko AS, Rochev YA, Gorelov A, Glynn TJ, J Fluoresc. 2010 Feb 24.  [Epub ahead of print].
 
Rissanen M,  Puolakka A, Ahola N, Tonry A, Rochev Y, Kellomäki M, Nousiainen P, Effect of Protein-Loading on Properties of Wet-Spun Poly(L,D-Lactide) Multifilament Fibers,  Journal of Applied Polymer Science,  Vol. 116, 2174?2180 (2010).
 
Gundy S, Manning G, O'Connell E, Ellä V, Harwoko MS, Rochev Y, Smith T, Barron V. Human coronary artery smooth muscle cell response to a novel PLA textile/fibrin gel composite scaffold. Acta Biomater, 2008 Jun 20. [Epub ahead of print]

Gallaher H, Carroll, W. M., Dowd, M. and Rochev, Y. (2008) The Effects of Vinblastine on Endothelial Cells , Endothelium, 15:1, 9 ? 15

E. McLucas, Y. Rochev, W.M. Carroll and T.J. Smith. Analysis of the effects of surface treatments on nickel release from nitinol wires and their impact on candidate gene expression in endothelial cells. Journal of Materials Science: Materials in Medicine. 2008 Mar;19(3):975-80. E.

Burke M, Clarke B, Rochev Y, Gorelov A, Carroll W , Estimation of the strength of adhesion between a thermoresponsive polymer coating and nitinol wire. J Mater Sci Mater Med. 2008, 19(5), 1971-1979.

M.Moran, W. Carroll, A. Gorelov, Y. Rochev, Intact Endothelial Cell Sheet Harvesting from Thermoresponsive Surfaces Coated with Cell Adhesion Promoters, Journal of the Royal Society Interface, 2007, Dec 22;4(17):1151-7.